In March 2006, Lamborghini unveiled a new version of its halo car at the Geneva Motor Show: the Murciélago LP 640. The new title incorporated the car's name, along with an alphanumeric designation which indicated the engine's orientation (Longitudinale Posteriore), along with the newly updated power output. With displacement now increased to 6.5 litres, the new car made 640 PS (471 kW; 631 hp) at 8000 rpm. The Murciélago's exterior received a minor facelift. Front and rear fascias were revised, and side air intakes were now asymmetrical with the left side feeding an oil cooler. A new single outlet exhaust system incorporated into the rear diffuser, modified suspension tuning, revised programming and upgraded clutch for the 6-speed "e-Gear" automated sequential transmission with launch control rounded out the performance modifications. Interior seating was also re-shaped to provide greater headroom, and a new stereo system formed part of the updated dashboard. Optional equipment is included Carbon fibre-reinforced Silicon Carbide (C/SiC) ceramic composite brakes, chrome paddle shifters and a glass engine cover.
At the 2009 Geneva Motor Show, Lamborghini unveiled the ultimate version of the Murciélago, the LP 670–4 SuperVeloce.The SV moniker had previously appeared on the Diablo SV, and Miura. SV variants are more extreme and track-oriented, and are released at the end of each model's production run.
The SuperVeloce's V12 produces 670 PS (493 kW; 661 hp) at 8000 rpm and 660 N·m (490 lbf·ft) of torque at 6500 rpm, thanks to revised valve timing and upgraded intake system. The car's weight was also reduced by 100 kg (220 lb) through extensive use of carbon fiber inside and out. A new lighter exhaust system was also used. As a result of the extensive weight loss, the SV produces a power-to-weight ratio of 429 bhp/long ton. Also standard were the LP 640's optional 15-inch carbon-ceramic disc brakes with 6 piston calipers.
Production of the Murciélago ended on November 5, 2010. Its successor, the Aventador, was released at the 2011 Geneva Motor Show.